I would just like to say I have been taking Ultracet for about 5 years with yearly blood tests. All my life I have suffered with RLS and now I have been diagnosed with Fibromyalga which is very painful and no one understands this pain unless they have experienced it. Ultracet has allowed me to function so much better and for all those years with RLS when I could not sleep at night and was so tired during the day ,Ultracet has changed all that .I have no side effects except for maybe dry mouth which comes with most medications. I take 4 or 5 Ultracets a day and have little or no pain. It has changed my life so much for the better.