I took Doxy as an anti malarial precaution. Worked fine, no physical side effects. Did get bitten by mozzies in a major endemic area in Nuigini but no Malaria. However, for the time I took the drug (and I did follow doctors orders for the full course) I was visited nightly by the most vivid and horrible nightmares that made it quite an ordeal to go to sleep. Now, I suffer no mental illness or take any mind altering substances. I have heard annicdotally that other people have endured similar side effects. Any other Doxy dreamers out there?