I took Prednisone for a cough (yes, just a normal virus!) for two weeks. I have been off of it for 5 days now, but I'm still having effects such as rapid heart rate (I'm seeing a cardiologist next week), acne, moodswings, and restlessness. I weighed 100 pounds when I started the pills and now I'm 106- that's a big gain for someone as small as me. I will never take this medication again.