I've had ulcerative colitis for about 12 years now and I have been on prednisone at least twice a year since. I've kind of gotten used to the feeling when I am on the drug and just deal with it. It is hard with the blurred vision, fatigue, sweating at night, and trying not to yell at my kids but I think I get by pretty good. I am currently on 60mg now and have been for about a month, I think the older I get the worse it is trying to deal with the side effects. I am experiencing all the side effects everyone has talked about and can wait until I start tappering off. Working out helps when I feel up to it. It's also hard trying to get my family to understand what I am going through.