Okay...I started the NR 48hrs ago...and so far...no depression or anything like that. I am however having these weird leg cramps. I didn't know if I should be concerned or if its your typical leg cramp. I am not one to try new things so this is kinda scary for me. I have always used the Depo shot...but quit taking them after forgeting to get them every 3 months...and then became pregnant. Now that I am back on birth control I thought this would be better than the pill. I will definatly not take any sign or sympton for granted. Thank you all for your postings...it will help lots of people.