Numbness, chronic weakness, chronic pain after 2 months of advair. I'm 47, never have gained weight. In one month gained 10 lbs! I feel horrible and sick all the time. Weird rashes-I never get rashes. I went to the doctor one month ago, she told me almost no chance that these were symptoms of this drug. I have been exhausted, and confused. My right thumb is always completely numb. I have terrible breast pain as well. Finally, I went to an accupuncturist that told me flat out that this drug causes permanent numbness in people and she firmly told me to get off it now, before it is too late. I hope it is not too late for me.