My doctor prescribed Lisinopril 20/25 in 2003 when my bp was 180/110. In September of 2006, I experienced a full blown panic attack. It was shortly after I had my left knee replaced in August. After this panic experience, I never seemed to recover from anxiety, and heart palpitations that were so crazy that I told my husband that I felt like I had just run a race. I experienced these palpitations every day and when they started, I started getting anxious. I thought that I was having these sensations because I was weak from the surgery. I experienced lightheadedness, and extreme fatigue, and blamed everything except the Lisinopril. My appetite has been poor and I force myself to eat only because I have to in order to survive Also, after the September panic attack, I felt like I was disconnected from reality - like someone posted earlier, a feeling like I was not all there. Awful feeling! A few months before these feelings, my present doctor (not the one who had prescribed the Lisinopril) told me to cut the Lisinopril in half because my bp was quite low. I did that but I still had the palpitations, etc. I never for one minute thought the Lisinopril was the culprit. Then about two months ago, I had a blood draw and it came up with a high level of potassium. It seemed at first that the lab had made a mistake, however, in a recent draw, I not only had an elevated level of potassium, but the calcium was elevated as well. My doctor called and told me to stop the Lisinopril. This is when I began to search the web for side effects, etc. Like a dumbbell, I never thought to question the Lisinopril. I have been off it three days now and the palpitations have lessened, however, I am still not back to my normal self but I hope that these effects will eventually go away. I have total empathy for all of the folks out there who have suffered these horrible, debilatating side effects.