I take 50mg daily. At first tingling in hands, and loss of taste of carbonates (like pop tasted flat all the time) that went away after a while. Lost weight, but gained it back within the year. When i drink alcohol I don't feel anything, even after several drinks, no hangovers. anyone else experience that? I can only guess its from the topamax, because I used to get terrible hangovers, and now I never do, and also I stopped taking it for a short while and while not on it I would get severe hangovers. NONE when on topamax. Has virtually changed my life on the otherhand, I used to get migrains DAILY! now I get them maybe once a month if that, and they are not nearly as bad.