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Has anyone on Lisinopril experienced upper GI problems such as...

Posted at 9:22 AM on Jun 12, 2007 by collie, #21755
Has anyone on Lisinopril experienced upper GI problems such as Achalasia, trouble eating, reflux, or getting food 'stuck' in the esophagus? My wife has lost 50 lbs in a year due to inability to eat from what was initially diagnosed as Achalasia (rare disease that affects the operation of the muscles in the esophagus and/or lower esophageal sphincter [LES] at the top of the stomach). However, Botox injections in the LES provided little relief which is not typical for Achalasia patients. She tests negative for Barrett's Syndrome and any form of Connective Tissue Disease (or arthritis). My MD recently put me on Lisinopril (another horror story); while I was researching the drug, I noticed that it could cause muscle weakness. My wife backtracked the date that she was put on Lisinopril and it coincided with the onset of her GI problems. While monitoring her BP several times a day, she has cut back to 1/2 dose and has shown a marked improvement in the last 10 days. (It is too early to say with certainty that Lisinopril is causing the GI problems.) Has anyone experienced similar problems?
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Reply about 1 year ago on Dec 13, 2007 by mnewnam, #3432

YES! I have been taking lisinopril for about 8 years now. I also take prevacid for acid reflux. The prevacid was prescribed AFTER I started taking lisinopril. Also, Allegra-D for allergies (probably the cough associated with this drug instead of allegries). Just had my prescription changed to Benicar this week and after 3 days the cough is going away and the stiffness/weakness in my legs is lessening. I'm going to wait until January to see how the Benicar is going and then stop the Allegra-D if the cough is completely gone. Next step is to stop the prevacid for acid reflux to see if I don't need that anymore either. So, the way I figure it I started taking lisinopril, then got prescribed Allegra-D for the cough, then prevacid for acid reflux. All conditions related to the first med I started taking. Thanks for posting!

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