I had to get a kenalog shot when I moved to another part of the state I live in because I was having trouble breathing. This was 12 years ago when I was 19. My breathing problem cleared up immediately and I didn't have any symptoms? Two years ago I developed some sort allergie that created blisters all over my legs from right above my knees down, they itched like crazy and the scratching I was doing was causing infection. I had to go on bactribin for 4 wks. The blisters came back almost immediately so my physician gave me a shot of kenalog and the ichting and blisters went away with in days. I did gain some weight and there were some cramps in my legs but the benefits (for me) far out-weight the problems before I took the shot.