I was diagnosed with asthma 2 years ago when I was 47. I take Allegra, Foradil, Asmanex, Singulair and receive two allergy shots a week. I also take a tiny dose of Buspar for anxiety. I have been on Singulair for somewhere from a year and a half to two years. Two weeks ago I started having what for me are very disturbing side effects that I felt sure were drug related. Twitching leg muscles, a terrible restlessness upon waking which causes sleepliness, heavy feeling in my chest, some headaches ( I never had them before). I have had tingling in my left hand for while and I thought that was because of something else, but now I am wondering....everything is definetly new since I started this drug, but most of it recent. I went off the Allegra, Buspar, Asmanex. I had no reduction in symptoms. At the end of the week I stopped taking the Singular for two days and started to feel better, but then decided that the symptoms were was caused by something else (hormones) and resumed all meds. The symptoms came rushing back. I now have ceased the Singular, but only for a day. I am narrowing the cause of the symptoms (which elsewhere in the literature seem to be very much attributed to a medication induced situation) and I am thinking it is the Singular, particularly after both reading all of your postings and talking to friends who either have had similar effects or have family members who have and after having no reduction in symptoms after going off my other meds. I will post again after a week to let you know if Singulair appears to be the culprit. Some people I talked to whose family members have had the same reaction said that there are plenty of other things available to help the asthma symptoms and quite frankly, as far as I can tell, the inhalers are what are working the best and this drug is not worth it if you are having side effects of this nature. Fortuna, I had the same idea as you, to get my heart tested and thought maybe I was heading for a stroke or something, but now I am convinced that this is medication related. Please post again and let me know how going off this drug is working out for you. I will do the same. The best to all of you.