I took Imitrex the first time and I thought I was going to freak out. WOW! My throat was tight and I was burning all over. Then my arms and legs hurt so bad I could not move. The headache went away after all of that. I did not try it again for a month and then I got another bad headache and I thought that I would try it again. It did the same thing to me. I thought that I was going to die. I promised the Lord if He let me live, I would never take another one. And, I am keeping my promise just as He did. There are better alternatives to headaches.