Acne, decreased libido, depression, inability to lose weight (even with exercise and dieting), among other side effects. I have never had an acne problem but not a week went by without major pimple outbreaks on my chin. Sex is totally unappealing and my decreased sex drive has really effected our marriage. Mood swings have not been fun. Also had some backpain that I can't understand. Had it removed today and it was a nightmare - the IUD had migrated and was way up high in my cervix, had to have a hysteroscopy to have it removed. I have had two vaginal deliveries and this was far worse than either of those. Painful, terrible cramping, thought I was going to pass out and I normally have a high pain tolerance. Would never recommend the Mirena IUD to a single person!