WOW - it's so great to feel like I may have found an answer! Been on Toprol for about 5 yrs due to palpitations and rapid pulse. Have gained about 20 lbs,. that WILL NOT COME OFF. My short term memory loss I chalked up to middle age, but you know what? It's bad - my kids think I'm getting senile at 53! It shouldn't be that bad. Could it be the Toprol? hmmmmmm