I recently had gum surgery and was prescribed dox. I am only taking 100 mg/day, but I've had extreme lethargy, headaches, itching, swollen lips, nausea and bouts of confusion and dizziness. I feel very sad on this medication and I'm usually a very happy person. I'm stopping the meds today, so hopefully I will be back to my normal self within the next week. I wish I had researched the drug sooner so that I could have stopped taking it earlier...I thought my reactions were due to the pain meds, but I was mistaken!!!