I have been on Advair for almost five years (on and off for three, but 2X a day for two 250/50). The the symptoms appeared: Tingling extremities, headaches, numbness of my limbs and all other symptoms mentioned above. I thought it was the statin drugs, so I stopped taking them. I still suffer from the symptoms until they continued to exacerbate. Lately, the nerve or muscle pains were unbearable at night. I went to my MD who reoommended X-Ray on my neck. Then I thought ADVAIR could be the culprit!!! Am I so relieved, I found this site. Now I am going to slowly wean myself from it. L.L.R. Hawaii