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I am 40-years-old and took Singulair for about two months. I fir...

Posted at 10:46 AM on Sep 04, 2007 by carried, #23372
I am 40-years-old and took Singulair for about two months. I first took it for about two weeks and got horrible symptoms and then stopped for a week and then tried it again for about a month. Never again will I put Singulair into my body. My symptoms were chronic and severe muscle cramps and twitching, restless legs, body aches, numbness, tingling, hair loss, weight gain, and skin changes (urticaria and angioedema). I also used to suffer from menorrhagia to where now I barely get a cycle. I cannot blame Singulair for the headaches/migraines because I have been a headache/migraine suffering for many years. When I first stopped taking Singulair the symptoms calm down. But since then they have come back with a vengence. I have been to several specialty doctors (family doctor first, endocrinologist, neurologist, allergist and rheumatologist). Now please let me defend myself by saying I see my family doctor and gynecologist yearly for a physical and also when I am sick and I have always been basically a very healthy, and slender woman with thick hair. I was on no other medications other than ibuprofen and acetaminophen for the headaches/migraines. What they have found so far is that I have secondary autoimmune hypothyroidism (only my TPO antibody and thryoglobulin are extremely elevated, but my TSH, T3 and T4 are completely normal), and allergies to everything outside (no food or pet allergies) and idiopathic lupus (because my skin has developed urticaria and angioedema). I am going for an EMG and MRI of the brain in one week because they are trying to rule out MS. They have been saying that my symptoms look like MS or lupus. They have ruled out lupus because my blood tests do not show lupus only my skin is acting like lupus. My allergist put me on doxepin for my skin and twitching symptoms. This medication has helped my skin and slowed down the twitching. I am not trying to blame Singulair, but it is very strange that I was a basically healthy person with some outdoor allergies and mild asthma. I would get pneumonia once a year also (always around the holidays). Now, I feel like crap since taking Singulair. My legs are the worst of all the symptoms along with the constant twitch under my right eye. This can drive a person insane, especially when you are trying to relax and your body cannot. Thanks for listening, Carrie
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Reply over 2 years ago on Sep 04, 2007 by twickle_purple, #1544

OMG, I can't believe you posted this just today! I am 43 (female) and have been on Singulair for a couple of months now and the benefits have been AMAZING! But recently I started to bruise, over every-little-thing, even a blood pressure cup created a ring of broken blood vessels. Then about 3 - 4 weeks ago I started getting deep lower leg pain, and cramping in my calves and arches. This grew more regular, and my hips joined in and I now rarely became without the pain and deep aches. I can barely type this my hands and forearms are so weak. Yesterday I couldn't pinch my fingers to pick up a potatoe chip! My arches are curled with aches, I am weak all over and getting really uncoordinated. It's getting so pronounced that I realized that this due to something I'm taking and the only thing I'm taking is Singulair so I decided to Google "Singulair Side Effects" and the first link I clicked was Carrie's post.

Carrie, did the symptoms stop when you stopped taking the drug? How long did you take it in total and how long have you stopped.

As of today I will no longer take this drug. Which is a very big loss for me, I have chronic generalized eczema and severe facial flushing. The Singulair was a s beneficial to me as my steroids were (different results). The side effects are not worth it, I can't function.

Corinna

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Reply over 2 years ago on Sep 13, 2007 by liz2, #1776

Dear Carrie, I just came home with a very expensive prescription for singulair and after reading all these side effects I have decided I don't need any more problems. I, too, have thyroid problems. I already have some things that resemble singulairs effects. Have you ever read "The Water Cure" Many people in our area (in Penna) and elsewhere have been cured of asthma, MS and many other things with this water cure. (Your Bodies Many Cries For Water) You can get info on website Watercure2.org. Good luck.

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Reply over 2 years ago on Sep 15, 2007 by faith9, #1814

Hi Carrie,
I have a similar history to yours (it's almost uncanny) but I think what caused your MS/lupus-like symptoms was the ibuprofen for your migraines-- not the Singulair. I took Advil almost every day for about four years (for headaches) and then stopped cold turkey for a month last year. A few months before I'd stopped, the skin rashs and mild extremity tingling had begun but were not problematic. Then, just after the month of stopping the Advil, I developed all sorts of horrible MS-like symptoms (though an MRI ruled out MS) which I suffer from still a year later. I did take Singulair for one week (because my breathing had become affected and I was suddenly diagnosed with mild asthma when the other symptoms appeared) but every symptom I had that you described was a symptom I already had. Inotherwords, it wasn't the Singulair. Not to say Singulair couldn't cause side effects, but if you took ibuprofen on a regular basis for a lengthy period of time, I really think that is the original cause of your symptoms. I'm still in the process of trying to relieve all of the problems that developed in the last year; there have been good phases followed by relapses (during which times I took Advil having not yet made this connection).
-Paula

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Reply over 2 years ago on Sep 30, 2007 by momof1, #2145

My 6 year old son started with symptoms in July, after having been on Singulair, and Advair for over 8 months. He had pain in his legs, arms neck,
hands, and feet. I took him to his pediatrician, she ordered blood work.
All came back negative. One day while my son was at school, on a hunch, I
decided to research his medications. I was amazed when I came across this site, and discovered my poor little boy was not alone. I originally discovered the side effects of Advair. I took him off of it immediately. I took this info to his doctor-- I was also told that these side effects were highly unlikely the problem. However, she had no other reasonable answer.. The doctor recommended I make an appointment with a neurologist for an EMG, and also my son had more bloodwork done to check for thyroid problems.
I took my son off the Advair 8-29-07. It's been 1 month I am slowly seeing improvements. I took him off the Singulair 2 weeks ago. I was just able to look this medication up today. I cannot believe how quickly things are turning around. I will not ever again put my son on any medication without
research. I do realize that not everyone will have the side effects listed. However, I wish that doctors would be more willing to investigate these claims-rather than treating you like an over reacting patient(or parent).
I actually had a doctor pull out her Physicians Desk Reference book and tell
me these side effects were not listed in that book, therefore they did not exist.
Mom of 1.

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