I started taking sulfameth last Tuesday. After today's first dose, I noticed that my face and chest started to become red and blotchy. I immediately regarded it as an allergic reaction to the pill and went to my doctor. He told me to stop taking the pill. Well, several hours later I have developed a rash that covers my face, chest, shoulders, torso and back...and who knows what will come next. The burning and itching and redness is intense and extremely uncomfortable. This medicine is terrible. Especially after reading all of these side-effect accounts. Not worth it.