I took my first dose at 9:30pm and an hour later felt wierd and a little shaky for two hours. The second day I took it at 10pm and by 11, I was shaking, cold tingly hands and feet,dizzy, throat swelling at the base inside out, breathing trouble,chest pain and heart palps, diareah, stomach pain, and my forehead was numb. By 4am I had to wake up my husband to rush me to the ER. I could not walk by myself... felt like I was going to black out. I still felt most of the symptoms only milder for the next few days.