I've been on Desogen for two months now and am switching to another pill. Biggest complaint is MAJOR mood swings. Angry, pick fights with my husband, cry for no reason, and the feeling that I can't stop myself once I'm set off. It's horrible! Only good thing is it made my breasts swell a cup size, but it was very painful. My gyno told me this pill and breast tenderness can be affected by caffeine. I'd rather give up the pill than my morning cup of java!