I'm 25 and have never had great skin, but I've found that minocycline will clear up my acne right away. That is, it used to, until I started with lamictal. Even with the minocycline plus tazorac and an antibiotic cream, my skin is breaking out on my face, especially at the jawline and outside of my face. But the really weird thing is that my back and chest are breaking out. That has NEVER happened before and it's not the infamous rash.
Other things I've noticed: sensitivity to computer screens and TVs, probably because my vision is getting worse, but so I get headaches; brutal periods with extreme breast tenderness; slurred speech and short-term memory loss at first, but not any more; occasional feelings of just being "out of it;" a bit of weight gain and I've always been superthin, but even with diet and exercise am having trouble maintaining my weight. Oh, also the nausea mentioned above, in the mornings; it was so bad I thought I was pregnant.
I'm only on 75mg/day at night for mood stabilization, but mostly because I take wellbutrin and had a seizure on it last year, though I'm not epileptic. I've always been sensitive to medications, and I have to say I've felt extremely "stable" on lamictal, but almost too stable. It's been a bit disorienting and I've felt my creativity diminish (I'm a writer). When I first started the lamictal I had also started a new job. This was a really bad idea as I couldn't remember any of the things my boss was telling me and my speech was messed up; I even stuttered a bit, which was scary.