I took Topamax for a week about four months ago for migraine. I stopped because I felt so dopey. It did help with the migraines and I noticed it mellowed me and evened out my mood. Despite that I don't suffer from any mood disorder.
Three days ago I started again because I had been experiencing frequent migraines. I am only in the 25mg at night phase and have already decided to quit again. The side effects are just too much. I awoke this morning and my extremities were completely numb.
After I showered, I caught myself just standing in the closet spacing out. I find it difficult to concentrate and focus (I was just staring out the window a moment ago!). I sound like an idiot when I talk to people and try to explain things. I left work early today because I was feeling so uneasy and depressed that I thought I was going to shake apart. That is totally unlike me. (I'm a cop) And this is after only three days back on at a minimal dose. So, I'm glad it works for some, but it's definitely not for me. The migraines are actually preferable.