I have just recently started taking topamax as of 4 days ago for severe migraines. Today was the first day I have actually had a soda and I was convinced that the pop I bought was flat but after reading this I now know that I am not crazy. I have also already experienced tingling in my hands, fingers, and toes, tightness in my chest, loss of appetite, one night of extreme anger, difficulty concentrating, and some depression. I am trying to figure out if this pill is actually worth it for me if I am already experiencing this many side effects this early. I am only on 25mg right now and I am supposed to increase to 100mg of the next couple of weeks.