First month I gained 20 lbs was at 600 mg had racing heart rate, restless legs and couldn't get up before I had slept 12 hrs. Medications works well for my bi-polar disorder and I still have my personality which some other medications seemed to have wiped out. Now I am down to 400 mg and am starting to have stomach pain, maintianing the same weight but no more restless legs or racing heart. Seroquel is the only medicine I am one and am starting to get sore stomach in the night. I have been on it for 4 months now.