I just recently started Topamax and had no idea of all the side effects that comes with it. So far I have been loopy, forgetful, have difficulty concentrating and etc.. The other bad side effect that I have had is my legs have hurt to the point that I was out of work for two days because I could barely walk. I couldn't lift myself up with my legs at all I had to use my arms. My arms and hands go completely numb at night and I wake up "looking" for them. I hope these all get better as my body adjusts to the meds. I haven't decided yet if the side effects are worse than the migraines.