I had my heart bypass at 35yo, 13 years ago. Since then I've been on a range of Cholesterol lowering drugs with low dose asprin (81mg). My reactons to the drugs were as follows:
1. Lipitor; memory loss, depression, muscle pain (afer a few months), nerve pain (after 9 months) - I reacted the worst to this drug.
2. Pravacol; Worse memory loss, muscle pain.
3. Simvahexal; Muscle pain.
4a. Zocor ; Slight muscle pain, no memory loss or depression (but apparently not good at lowering cholesterol evenly over 24 hours).
4b. Ezetrol 10mg (took this whilst on Zocor); Pain in ascending colon. This may have been because I was taking asprin at the same time.
At this point I stopped taking asprin, and started taking Plavix to thin my blood (about 3 months ago). I noticed that I was no longer getting constipated and didn't have a constant discomfort in the small intestine I was getting whilst on Asprin.
5. Crestor 10mg; Good cholesterol lowering, but slight but continious upper stomache pain (excess acid I suspect). Occassionaly waking up gasping for air.
6. Crestor 20mg; Took this for 3 days before waking up at night gasping for air, and gaining no relief in breathing harder. Went to hospital, they couldn't find anything wrong (I was gasping for air whilst I was being attended to, so it wasn't sleep apnia). I noticed it go worse when I was relaxed, and disappeared if I was walking or alert. As the only thing that had changed in the previous few days was the increase in my Crestor dose, I decided to switch back to taking 10mg dose. The severe breathing problem went away. I noted on the packet that breathing problems are an allergic reaction to the pill (but I wish they had given more details about the characteristic signs - no one in the hospital thought that it might be a reaction to the Crestor).
7. I think I'll try Ezetrol with Crestor 10mg; As they work in different ways, I'm hoping they will improve my lipid profile, which is good, still not ideal.
I've also been taking 4g of Omega-3 fish oil each day (2g twice a day), which I think is helping to restore my memory, and also slightly imprives my lipid profile.
Looking for sometthing now that will increase my HDL, which apparently prevents the LDL Cholestrol from sticking to the sides of your arteries, from where it gets sucked under the inner lining, narrowing the artery.
Some interesting reading regarding the new frontiers in the reduction of heart attacks and strokes is at:
http://www.theheart.org/article/114321.do
Correction to link regarding HDL developments:
http://images.google.com.au/imgres?imgurl=http://www.theheart.org/displayItem.do%3FprimaryKey%3D113939%26type%3Dimg&imgrefurl=http://www.theheart.org/article/114321.do&h=457&w=470&sz=41&hl=en&start=4&um=1&tbnid=SW-3K3FxwQFPNM:&tbnh=125&tbnw=129&prev=/images%3Fq%3Dcholesterol%2Bhdl%26um%3D1%26hl%3Den%26client%3Dfirefox-a%26rls%3Dorg.mozilla:en-GB:official%26hs%3DcDb%26sa%3DN
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