I've been on Wellbutrin with a lot of success for almost 8 years now. It took several weeks of experimenting to find the right dose. Too much or too little had similar effects increasing my anxiety. Missed does constantly exaserbated the problem until I started XL. Shortly after starting I noticed a change in my sexual response --it just took a lot more to "get me going." That subsided somewhat after awhile, but I've also used Viagra about half the time. My mood improved but continued to fluctuate. My Dr. added a small dose of Zoloft a few years ago and I noticed a significant improvement in mood. Finally, a small dose of Ritiln had a major effect on a root ADD problem. I have felt more stable, confident and productive ever since. However, my sexual responses has decreased again in recent months. Viagra has even become unrreliable. I am going to ask the Dr about going off Zoloft, but talk of permanent effects are worrisome. PS; regarding hair--not a big problem, though it is thinner now since 1999. Never mind that i'm 52 now!