I am glad to see I am not crazy!! I started on advair a week and a 1/2 ago. My blood pressure went up and after 6 days of taking advair my bp was 140/99. Heart rate increased from 60's-low 70's up to mid 80's. I have always had really good bp before this and a good heart rate. I also had weird sensation in my arms and legs and a tightness in my chest that would come and go. I had a headache pretty much the whole time I was taking advair. I had horrible cramps in my feet and legs. I also had something strange happen to my face. I got a strange pain in my cheek that went up to my eye feeling like there was severe pressure behind it and then after making my eye water it went back down to my cheek for a minute and then disappeared. I was starting to get really creeped out by all these things happening so I bought a bp machine and monitored my bp. 48 hours after stopping advair my bp was excellent (106/66), heart rate back to the 60's, no more weird sensations, headache is gone, no cramps in my legs/feet, and my crappy mood has improved. All these strange symptoms are gone! I will never take that crap again!! It may work for some but it didn't work for me.