Hi, I take Effexor, and have experienced many of the negative effects described here, however, my personal depression was such before I began that for me it was life-saving. During those periods when I've taken breaks from Effexor, withdrawal wasn't pleasant, nor was it quite as bad as some have experienced (I didn't get the brain-freezes or violent impulses). However, I did find an excellent post in another forum about tapering off, so I am cutting and pasting it here. (fyi, if you take 150s rather than 75s -- I take 150s -- you can use a similar schedule to open the capsules and shake a bit out rather than completely eliminating a dose):
In Response To: Re: New to Effexor (Sharon)
I'have been taking Effexor since one year and a half ( I take 225 mg per day). Before taking it, I was so worrying and panic that I could'nt do anything. It took me about 6 months before seeing a change in my mind. Now, I am very happy and I don't worry about everything anymore. It is a very good medication for me, though it decreases libido. I am reducing Effexor since two months this way : first week : after 7 days, I escape one pill (75 mg); then after 6 days, I escape one other pill and then after 5 days, one other, and so on. I wait about 2 weeks before beginning again for another 75 mg. It is the best way to get off of the med because if I try to stop suddenly, its horrible. Its the only disadvantage of this drug. I hope these comments will help you.