36 yr old female. Was started on Toprol -XL in Sept 07 during my angiogram to relax my heart and lower my heart rate. Have also been on Lisinopril for several years prior for hypertension. Since starting the Toprol, I have had increasing depression, lethargy, shortness of breath, chest pains that have worsened, my feet are FREEZING all the time, I have gained 17.5 pounds, my fasting blood sugar is now up to 160-170 range, I have had many headaches (like the kind you get when your BP is sky high) and the other thing I have noticed is that my BP is bouncing ALL over the place. Last week it was down to 90/54 and I felt horrible. Then it will go up to 140/99(ISH). Find it really hard to finish my own sentences lately, and if I had nothing else to do, I could easily sleep 12-16 hours a day-everyday. I am down to 12.5 mg a day, and will be speaking to my cardiologist about this asap, had NO idea that Toprol could have been the culprit until I was told about this site. Thank you to everyone for sharing their stories, and good luck and blessings to all.