I had been on Toprol XL 50 mg. for three years. In April of this year, I began having gastrointestinal problems. By May, I was sick just about every day with gas, bloating, cramping, pain and nausea. I was seeing a gastroenterologist practice almost weekly. Over the next five months, I had just about every test, scan, and scope there was to do to no avail. By June, I began having anxiety attacks simultaneously with the gastric episodes. The doctors could find no reason for the symptoms and I was referred to another specialist and tests that were ordered at a medical facility 50 miles away. I had also lost 38 lbs. because I was unable to eat without becoming sick. In November, I notice that my hair was thinning and my family doctor said that it could be from the Toprol. At that point, I discovered this website and began reading the postings. I cut the Toprol dosage in half after informing my doctor about it. In three days, I started to feel better. I also read more of the postings and saw that other were fine on the brand name Toprol but had problems with the generic. Click went the light bulb. Towards the end of March of this year, I had been switched to the generic. I began weaning myself from the medication and took the last dose on Thanksgiving. There have been some minor withdrawal symptoms but I am feeling so much better and have had no gastric symptoms for two weeks. Yesterday, I was actually hungry for the first time in months. I saw both the family doctor and gastroenterologist and informed them that they need to consider a patient's medications which unexplained illnesses arise. I can't express the gratitude that I feel for having located this website and thank everyone for the information that has been provided.