I felt the same as many of you, a little heart fluttering, never have this usually with any other medications. Nervousness, but also could be caused by reading too much about the medication, etc. I felt very tired, again could be caused by sinus infection, but very lethargic, couldn't turn off brain as someone mentioned above, very good analogy, exactly how I felt. The taste is unbearable alone and then I am not sure if this is connected, but I discover a bump on the back of my tongue, which made me feel funny swallowing, after taking medication for 3 days, and called pharmacy, b/c of symptom , they told me to lay off of it, horrible feelings!