I have been taking Wellbutrin 150mg 2x per day since 1996. It has been an absolute lifesaving experience. Yes, I do have some memory loss, but not enough to alter my life at all.
The one serious side effect, and a great one at that, is the heightened feeling of ecstasy during an orgasm. Oh my God, prior to Wellbutrin, I was a 28 year old male, who totaling lost interest in sex, and had almost no pleasure whatsoever when I orgasmed. Now, when I orgasm, the feelings of pleasure are so intense, at times, I honestly think I am going to have heart failure.
It is by far the most incredibly gratifying sensation I have ever had. I stopped Wellbutrin several times over the past 11 years, and each time I was back to my old self with 48 hours. One other positive side effect for me, it has cured my "lactose intolerance". I have been eating all the dairy I could ever want without any problems or discomfort whatsoever. However when I stopped the Wellbutrin, my lactose problem returned within 24 hours.
As I told my doctor, if he were to tell me I would live to be 90 without Wellbutrin and old to 60 with Wellbutrin, I would chose the 60 years. Thats how much more enjoyable life has become for me. I would not ever want to stop taking it. It has saved my life. One last thing, I forgot to mention, it has treated my depression incredibly well also. Again, it saved my life.
Everyone is different. I believe that if you are experienceing bad effects from the Wellbutrin therapy, then you probably don't have a chemical imbalance at all, or you may be taking too much and sending your chemicals out of balance in the otther direction. One must carefully considering perhaps reducing or increasing their dosage depending on their personal situation. Always discuss it with your doctor of course, this drug is nothing to mess around with. I think it is very powerful, and a Godsend.
Best regards to all.