The problem I had with this drug is that it's only good for small sinus infections as far as I've experienced. It was clear after the first time I took this drug that it took two weeks instead of the usual one week treatment to get the sickness under control. And then when I started getting constant sinusitis this drug didn't work for me at all. For sinus infections I prefer taking Levaquin, it works better for me. (They usually only prescribe this to adults - it's not intended for children as strong as it is, but it all depends on the individual person.) I wouldn't recommend Zithromax for severe or constant sinus infections.