Took it as a precaution for a dental surgery. I wound up having severe reflux (which resulted in throwing up one night) and the most severe heartburn I can imagine. I took it before I went to bed, which I found out is a no no, and was unable to sleep due to the burning in my throat and chest. I haven't taken the pill in over 12 hours and my chest is still burning pretty bad. I usually tolerate medicine very well. I will be asking my doc to take me off of this....