I was put on Avelox and went on a cruise. Well on the third day of taking it I broke out in hives, had difficulty breathing, could not walk, the pain in my legs were so bad and had a burning sensation from my nose to my pelvis. I felt like I was on fire inside my body. Well, the doctor on the cruise ship gave me many medications to combat the allergic reaction and thankfully I was fine after that. I still to this day have severe joint and muscle pain. I didn't realize until I read all this that it could have been due to the Avelox. I was on Avelox, Cipro, and Levaquin also for a sinus infection. That was Aug. 2006 and quess what still feel like crap with the pain in my legs and feet.