I started taking Prednisone in late November for inflammation of my lungs, a complication of influenza A. I started at 50 mg daily, then went to 75, then was hospitalized and went to 160 intravenously. After about a week, I was reduced to 120 then 75 by mouth a few days later. After 15 days in the hospital, I was released only to come back two days later with internal bleeding. I was released two days later and my doctor knocked several days off my withdrawal plan. About midway through all this, I started having a constant mild headache. After my second release, the headache started to get worse. The headache became debilitating and I spent some time in the ER where codeine helped. (I'm allergic to morphine which would have been their choice). The codeine helped for a day or two, but when I got to 60mg of codeine with no effect I gave up on the pills. My doctor gave me some sort of anti-inflammatory shot which helped.
I've been off Prednisone now for over a week and still have a constant headache, but most of the time it's not bad and only moderate at times. On average I see a gradual improvement.
I have had increased appetite and energy (in the beginning) followed by face and neck swelling, headache, nausea, blurred vision, internal bleeding and large muscle weakness.
I know that I needed something to stop my lung inflammation, but the cure has been worse than the disease at this point.