I was on Yasmin for about 10 days and wound up with severe depression. I was fine to begin with. I woke up one morning and felt a very hopeless, "don't want to do anything, don't want to get out of bed" feeling. All of these effects on vacation, too! I continued to take the pill for about another 3 days and continued to feel depressed and hopeless about 3 hours or so after I'd take the medication. The feeling was very distinct and it was clearly the symptoms of a depressed person (had to force myself to get out of bed, felt there was no reason to live). I felt like I had a black cloud over my head!!! I was also very irritable and angry with my family....for no reason. I also experienced severe nausea. I felt like I was experiencing morning sickness (and I know morning sickness....I have kids). I went off of the Yasmin and am now starting to feel myself again. I don't know the half-life of this med., but thank goodness I went off it sooner than later! I would take this product off the market or put a severe warning about anxiety and depression on the label!