My husband just started taking Vytorin again after about 2 to 3 months of being off of it-because of the cost of the prescription. He started developing severe back pain. He has had spinal fusion 10 years ago and it was so severe he felt like one of the rods had broken. Pain is now a little better after a few days, but he still can't stand for anyone to move in the bed when he is sleeping. After finding this site I am tempted to have him quit taking Vytorin for awhile and see if the pain subsides. He says he hurts worse at night after taking the medicine.