I was taking remeron sol-tabs (15mg) once at night for mild depression and inability to sleep. I have gained about 15 lbs. I stopped taking 3 weeks ago.....and have had extreme irritability ever since......Very disturbing.....But frankly...I would rather be irritable than continue to gain weight.....Bad news this drug.....they say I am in a minority....but I believe that is not the case...I have seen too many people post issues w/ weight gain.....Being and getting fat is depressing........