I was prescribed Levaquin 750 mg 1 a day for ten days. On the fifth day I woke up with both knees swollen and extremely painful. I did not connect the pain to the Levaquin and took two more doses at which time my knees were so painful I had trouble getting up from a chair and walking. My wrists were beginning to hurt and I had developed a deep rattling cough. I went back to my doctor who sent me for an MRI of my right knee. The result is that I have almost total loss of cartilage and suspected torn medial meniscus. My doctor says I probably need a knee replacement. I continue to hurt and now my feet and hands hurt and pop as well as my knees. I believe that this drug should be contraindicated in anyone with arthritis. I am very worried as I feel this pain spreading all over. It has been about 3 weeks since I stopped the Levaquin and I feel miserable, waking up 2, 3,or 4 times a night in pain.