I am new to Loestrin 24. I am 26 and have been on Ortho Tri-Clyclen since I was 16. I recently switched to a new GYN, who suggested I try Loestrin. She gave me 2 free samples, so I thought it was worth a try. Besides, I'd heard good things (on the commercials - of course). Immediately, I started noticing breakthrough bleeding, which I'd never experienced before. That lasted for a couple weeks. It was so annoying! I couldn't stand never knowing when it would happen. This past week was supposed to be my period. I knew that it would be shorter, since Loestrin has the 3 extra "active pills". But my period never came. I just started my second pack last night. I went on this site, to see what the real side effects of this pill are - the ones they don't publish on their website (before I completely freaked out). I have read that many other women have experienced no period, which made me feel a little better. I guess I won't run out and get a pregnancy test. One person asked why this was a problem, but when you're trying very hard NOT to get pregnant, a missed period hardly seems like a good thing. I need that reassurance every month that lets me know things are ok. I also have noticed weight gain and increased acne - which I didn't think to connect to Loestrin, but I'd never experienced that on Ortho. Some of these other side effects are downright scary and I'm now considering switching back to Ortho before the anxiety, mood swings and other things start!