On Advair for about 4 years, at first I was fine with only minor throat irritations. About a year later I started having the Leg cramps / Muscle tightness. I've been to many Doctors who couldn't explain my leg pain. I tried to stop using my Advair many times, but felt so horrible that I had to start using it again. Last week my allergy doctor put my on Prednisone for pleurisy and I decided on my own to GET OFF ADVAIR. I have felt like a new woman this week. My leg pain is almost gone, my eyesight seems to be improving, and my random joint pain is slowing down. I didn't realize until I found this site tonight, that SO MANY people have had the same experiences. Like you others, my DOCTOR assured me there weren't ANY side effects. I'll gladly use my inhaler a couple times a week to manage my asthma. DON'T listen to your DR, there are other ways!!!!! By the way, I'm a 38 year old female. I feel like I'm finally getting my life back.