I was on Zoloft for 3 years. While it helped with my anxiety, I sometimes felt it increased it. My biggest complaint was the weight gain. Over the 3 year period, I gained 35 pounds. While still on it, I did South Beach for 3 months and lost 5 pounds. =(
Last summer, I worked out 6 days a week for 1- 1 1/2 hour a day for 2 months. I didn't lose a single pound! My size 12's were still fitting pretty well. I have never weighed this much in my life. I was never even over a size 7.
I got off the Zoloft in October and have actually gained 7 more pounds since. It is really depressing. I think the company should have to pay for a gym membership or personal trainers! =)