I've been on Loestrin 24 fe for a little over 4 months now. I haven't noticed any mood problems. However, the first month I had very, very light spotting when I should have had my period. I have not had any bleeding since that time...no spotting or bleeding at all. I have also had pretty significant skin break outs since starting this pill. It is terrifying not having a period, but I think I'd rather not have one than belld 3 out of 4 weeks like I did on Yaz.