My daughter is ten years old and has had breathing problems since she was born, diagnosed with asthma/RAD when she was 2 or 3. She has been on several different medications since two or three including Singulair. To date she has been diagnosed with osteochondritis dissecans(bone necrosis in her knee), recurrent UTI's with kidney reflux and had a deflux surgery a few years ago, cold urticaria (hives when her body temperature is rewarming and vision problems. We just recently switched her Advair discus to a regular Advair inhaler with a spacer because her voice changed and had swollen tonsils for over two months. She has had stomach pains forever which I thought was from bladder infections but they are now getting worse with vomiting. After a few years I strongly believe that it is not from her bladder infections because she always has a trace of nitrates in her urine whether she has stomach pains or not. After reading the listings on this site I am definitely looking into this further. She has always had a very hard time with her emotions and anxiety and been very frustrated in not being able to control it. She gets headaches a lot. she also gets extremely bad cold sores. I am positive that these drugs we give are children need more long term studies to learn the short and long term-side effects. It is very frustrating to me that all these people have very similar side effects and nothing is being done. I just spent last night in the emergency room with my daughter having horrible stomach pains and vomiting again. No fever, normal stools etc. I will definitely be bringing this up ar our next doctor visit and be writing the manufacturer. Good luck to everyone out there. I sure hope some studies will be done soon and that we can find an answer to our problems. God Bless You All!