I have just taken my last dose and ever since I started it I haven't slept. I am so tired but just can't sleep. It's bad enough that I'm an insomniac anyway and this has just made it worse. I also have pain in my knees. If i sit with them bent they hurt and if i lay with them straight my legs start getting numb. Has anyone had this experience? My back aches all the time now. I have also had the constipation that goes along with it.