I've been taking Niaspan for several years and have had occasions...

I've been taking Niaspan for several years and have had occasions of flushing that wakes me up at night but nothing really dramatic. What I have learned is that taking the aspirin a half hour before the Niaspan is crucial. Last spring I hurt my knee, and my MD suggested that I take Naproxen sodium for awhile and skip the aspirin at night before the Niaspan. And surprise! I had flushing every night...until I realized that the aspirin really had made a difference! Now I make sure to take it and no more flushing. (The itching sounds awful...I sympathize with all who have that.)