After suffering from terrible skin from about junior high, I finally got a good enough job so that I had insurance to pay for a dermatologist. After heavy antibiotics and Retin A, I was given Accutane. In the next 3 months I suffered through: Severe dry skin and chapping, my hair fell out in clumps, my fingernails curled like parrot beaks, terrible muscle pain, severe depression (even though I didn't realize it until I was off of it), and of course the scarlet leather facial skin that "showed the drug was working".
Then after all that, shortly afterward my grandfather's Type 1 diabetes appeared in me (at age 40!). This warning about getting diabetes was NOT in the warnings that I had to sign off on then, but it IS now (funny, huh?). The kicker is, that after all that, I didn't even have acne. A better doctor correctly diagnosed me with Rosacea, gave me a simply lotion (Metrolotion), and my face has been fine ever since.
Stay AWAY from this drug!!!