After starting Januvia, I started having severe muscle pain along the lines of lactic acid burning pain when doing anything that used my muscles. I also developed creep crawly restlessness in my muscles. I also felt like I had the flu and my sinuses were swollen and had bloody drainage. After I went off Januvia, these symptoms gradually subsided. I went back on it and after two days on it all the symptoms came back and I feel like I have the flu. My muscles scream with burning pain that is really intolerable. If I walk anywhere, I have to keep stopping an giving my muscles time to recover before going on a little further. That's it for Januvia.